ICCBS Patents test

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 International Center for Chemical and Biological Sciences (ICCBS)
(H.E.J. Research Institute of Chemistry and
Dr. Panjwani Center for Molecular Medicine and Drug Research)

University of Karachi, Karachi-75270
Pakistan
   
ICCBS PATENTS
Last Updated: 3rd August 2021


 
 
US- Granted Patents
 
 
S. No. Patent Details
  1.  
Isoxylitones Mediated Neurogenesis; Atta-ur-Rahman, M. Iqbal Choudhary, Farzana Shaheen, Shabana Usman Simjee, Saba Majeed, Anila Bashir, and Kanwal Iftikhar; US-Patent No. 11,065,211 B2, Application No. 15/934,539, Patent Date: 20/07/2021.
  1.  
Nanosensor for the Determination of Insecticide; Muhammad Imran Malik, Muhammad Raza Shah, Sana Rahim, Sadia Khalid, Muhammad Iqbal Bhanger, and Muhammad Ismail Vohra; US-Patent No. 10,883,928 B1, Application No. 15/991,800, Patent Date: 05/01/2021.
  1.  
Food Supplement to Alleviate Symptoms of Parkinson's Disease; M. Iqbal Choudhary, Atta-ur-Rahman, Atia-tul-Wahab, and Humaira Zafar; US-Patent No. 10,849,953 B1, Application No. 16/447,819, Patent Date: 01/12/2020.
  1.  
Obesity Treatment; M. Iqbal Choudhary, Sammer Yousuf, Misha Siddiqui, and Madiha Mukhtar; US-Patent No. 10,765,716 B2, Application No. 15/671,191, Patent Date: 09/08/2020.
  1.  
Synthesis of C Resorcinarene Based Novel Amphiphilic Supramolecular Macrocycle as Nano-Scale Drug Loading System; Muhammad Raza Shah, Imdad Ali, Heyam Saad Ali, Babiker M. El-Haj, and Muhammad Imran; US-Patent No. 10,751,285 B1, Application No. 16/412,252, Patent Date: 05/08/2020.
  1.  
Anticancer Peptides; Farzana Shaheen, Muhammad Nadeem-ul-Haque, Shabana U. Simjee, Aqeel Ahmed, Almas Jabeen, Zafar Ali Shah, and M. Iqbal Choudhary; US-Patent No. 10,550,155 B1, Application No. 15/937,281, Patent Date: 04/02/2020.
  1.  
Anti-Obesity Effect of Borago officinalis Linn. Extracts to Prevent and Treat Metabolic Disorders; M. Iqbal Choudhary, Sammer Yousuf , Misha Siddiqui, and Madiha Mukhtar; US-Patent No. 10,426,806 B1, Application No. 16/007,130, Patent Date: 10/01/2019.
  1.  
2, 4-Dinitroanilino-Benzoic Acid: Novel Insulin Tropic Agent for the Treatment of Diabetes; Humera Jahan, M. Iqbal Choudhary, Mehwish Manzoor, Khalid M. Khan, and Atta-ur-Rahman; US-Patent No. 10,183,000 B1, Application No. 15/682,623, Patent Date: 01/22/2019.
  1.  
Bio-active Antioxidants from Plant Foods for Nutraceutical Product Development; M. Iqbal Choudhary, Juveria Siddiqui, Ahmed Abbas Khan, Suad Naheed, Achyut Adhikari, Jalaluddin A. J. Awlia, and Atta-ur-Rahman; US-Patent No. 10,005,809Application No. 13/759,820, Patent Date: 26/6/2018.
  1.  
α-Glucosidase Inhibitors; Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, Assem Barakat, M. Iqbal Choudhary, and Sammer Yousuf; US-Patent No. 9,802,894 B2Application No. 14/868,994,  Patent Date: 10/31/2017.
  1.  
Process for the Preparation of Quinoline Based Ionic Fluoride Salts (QUFS); Abdul Hameed, Nafees Iqbal, Jamshed Hashim, Khalid M. Khan, S. Tarique Moin, Shakeel Ahmad, S. Abid Ali, Fatima Zahra Basha, Mariya Al-Rashida, Rima D. Alharthy, and Shahnaz Perveen; US-Patent No. 9,643,169 B1Application No. 15/158,867Patent Date: 05/9/2017.
  1.  
Drug Repositioning: Urease Inhibitory Activity of (2S)-1-[(2S)-2-Methyl-3-Sulfanylpropanoyl]Pyrrolidine-2-Carboxylic Acid (Captopril); Jalaluddin Azam Jalal Khan, M. Iqbal Choudhary, Maryam Abdu Abdullah Al-Ghamdi, Etimad Huwait, Atia-tul-Wahab, and Samrah Iqbal; US-Patent No. 9,688,628 B1, Application No. 15/051,077, Patent Date: 06/27/2017.
  1.  
Myrtocomuloacetalone 1 As An Anti-Inflammatory Agent;  M. Ahmed Mesaik, Samreen Soomro, Farzana Shaheen, Noureen Khan, Zaheer Ul Haq Qasmi, Sobia Ahsan Halim, and M. Iqbal Choudhary; US-Patent No. 9,701,690 B2, Application No. 14/219,875, Patent Date: 07/11/2017.
  1.  
Diethylammonium Salts of Phenyl-Substituted Thiobarbituric Acid as Anti-Diabetic Agents; Assem Barakat, Mohamed Ali, Abdullah Mohammed Al Majid, Sammer Yousuf, and M. Iqbal Choudhary; US-Patent No. 9,527,820 B1, Application No. 15/147,878Patent Date: 12/27/2016.
  1.  
Schiff Bases of Thiazoles: A New Class of Ureases Inhibitors; M. Iqbal Choudhary, Ajmal Khan, Khalid M. Khan, Nida Ambreen, Atia-tul-Wahab, and Atta-ur Rahman; US-Patent No. 9,447,057 B2Application No. 14/310,738,  Patent Date: 09/20/2016.
  1.  
Modulation of c-FOS and BDNF Protein Expression in Pentylenetetrazole-Kindled Mice following the Treatment with Novel Anti-epileptic Compound HHL-6; Shabana Usman Simjee, Sabira Begum, Saima M. Malhi, Huma Jawed, Nadeem Ashraf, Farina Hanif, Bina S. Siddiqui, and Farhat Zubair; US-Patent No. 9,272,998 B1, Application No. 14/607,880, Patent Date: 03/01/2016.
  1.  
Anthranilic Acid Derivatives: Novel Inhibitors of Advanced Glycation End Products (Ages) Formation; M. Iqbal Choudhary, Humera Jahan, Khalid M. Khan, Amber Atta, and Atta-ur-Rahman; US-Patent No. 9,381,182 B2Application No. 13/968,071Patent Date: 07/05/2016.
  1.  
Inhibitors of Advanced Glycation End-Products (Ages) Formation; Humera Jahan, M. Iqbal Choudhary, Zarbad Shah, Khalid M. Khan, and Atta-ur-Rahman; US-Patent No. 9,387,198 B1, Application No. 14/634,045, Patent Date: 07/12/2016.
  1.  
Thiourea Derivatives; M. Iqbal Choudhary, Saba Farooq, Khalid M. Khan, Farzana Naz, Atia-tul-Wahab, and Atta-ur Rahman, US-Patent No. 9,387,186 B2Application No. 14/285,213, Patent Date: 07/12/2016.
  1.  
Treatment and Inhibition of Protozoal Diseases with Nandrolone and Its Derivatives; Elias Baydoun, M. Iqbal Choudhary, Atia-tul-Wahab, Colin Smith, Martin Karam, Dina Farran, Mahwish Shafi Ahmed Khan, and Malik Shoaib Ahmad; US-Patent No. 9,173,888 B1Application No. 14/289,395Patent Date: 11/03/2015.
  1.  
Small Molecule Activators of HSIV Protease for Development of Novel Antimicrobials; M. Kamran Azim, Yasmeen Rashid, and Khalid M. Khan; US-Patent No. 9,119,857 B2Application No. 13/919,665, Patent Date: 9/1/2015.
  1.  
Artonin I to Treat Resistant Infectious Staphylococcus aureus; M. Iqbal Choudhary, Saba Farooq, Atia-tul-Wahab, Christian D. A. Fozing, and Atta-ur-Rahman; US-Patent No. 8,889,733 B2, Application No. 13/740,919, Patent Date: 11/18/2014.
  1.  
3-Amino-2-(4-Nitrophenyl)-4-(3H)-Quinazolinone or Derivatives Thereof For Treating Or Preventing Antiviral Infections; Sheikh Riazuddin,  Osman Ali, Usman Ashfaq, Shaheen N. Khan, Javed Akram,  Atta-ur Rahman, M. Iqbal Choudhary, Khalid M. Khan, and Zulfiqar Ali  Khan; US-Patent No. 8,809,354 B2, Application No. 13/341,989, Patent Date: 08/19/2014.
  1.  
Anticancer Compound; Saif Ullah, Saifullah Khan, Azizuddin, M. Kashif, Ahsana Dar, and M. Iqbal Choudhary; US-Patent No. 8,389,501 B2, Application No. 13/184,548, Patent Date: 03/05/2013.
  1.  
Antitubercular Alkaloid; Sabra Begum, S. Nawazish Ali, and Bina S. Siddiqui; US-Patent No. 8,420,660 B2, Application No. 13/035,756, Patent Date: 04/16/2013.
  1.  
Steroidal Antitubercular Compounds; Bina S. Siddiqui, Nasima Khatoon, and Sabira Begum; US-Patent No. 8,389,503 B2, Application No. 13/037,494, Patent Date: 03/05/2013.
  1.  
Method of Producing Tibolone Metabolites by Fermentation with Fusarium lini; Atta-ur-Rahman, M. Iqbal Choudhary, Syed Adnan Ali Shah, and Shamsun Nahar Khan; US-Patent No. 8,148,558 B2, Application No. 13/015,554, Patent Date: 04/03/2012.
  1.  
Formulations Against Cutaneous Leishmaniasis; Atta-ur-Rahman, M. Iqbal Choudhary, Sammer Yousuf, Samreen Khan, Farooq R. Soomro, and Shahida Perveen; US-Patent No. 8,287,921 B1, Application No. 13/189,509, Patent Date: 10/16/2012.
  1.  
Method of Producing Tibolone Metabolites by Fermentation with Gibberella fujikuroi; Atta-ur-Rahman, M. Iqbal Choudhary, Syed Adnan Ali Shah, and Shamsun Nahar Khan; US-Patent No. 8,148,557 B2, Application No. 13/015,559, Patent Date: 04/03/2012.
  1.  
Anti-inflammatory Compound; Saif Ullah, Saifullah Khan, M. Ahmed Mesaik, Zaheer-ul Haq, Almas Jabeen, Sobia Ahsan Halim, and M. Iqbal Choudhary; US-Patent No. 8,329,678 B1, Application No. 13/184,551, Patent Date: 12/11/2012.
  1.  
Method of Producing Tibolone Metabolites by Fermentation with Rhizopus stolonifera; Atta-ur-Rahman, M. Iqbal Choudhary, Syed Adnan Ali Shah, and Shamsun Nahar Khan; US-Patent No. 8,148,556 B2, Application No. 13/015,551, Patent Date: 04/03/2012.
  1.  
Method of Producing Tibolone Metabolites by Fermentation with Cunninghamella Elegans; Atta-ur-Rahman, M. Iqbal Choudhary, Syed Adnan Ali Shah, and Shamsun Nahar Khan; US-Patent No. 8,198,041 B2, Application No. 13/015,553, Patent Date: 06/12/2012.
  1.  
7-Nitro-2-(3-Nitro Phenyl)-4H-3,1-Benzoxazin-4-one or Derivatives Thereof for Treating or Preventing Antiviral Infections; Shaikh Riazuddin, Atta-ur Rahman, Usman Zafar, M. Iqbal Choudhary, Usman Ali Ashfaq, Khalid M. Khan, Tayyab Husnain, Zulfiqar Ali Khan, and Javed Akram; US-Patent No. 8,148,368 B2, Application No. 12/876,999, Patent Date: 04/03/2012.
  1.  
α-Glucosidase Inhibitors from Lichens; Vinitha Moolchand Thadani, Shamsun Nahar Khan, Veranja Karunratne, and M. Iqbal Choudhary; US-Patent No. 7,867,989 B2, Application No. 11/767,465, Patent Date: 01/11/2011.
  1.  
Anticonvulsant Compounds; Atta-ur-Rahman, M. Iqbal Choudhary, Farzana Shaheen, Shabana U. Simjee, A. Ganesan, and A. Mohsin Raza; US-Patent No. 7,399,888 B2, Application No. 11/307,251, Patent Date: 07/15/2008.
 
 
US-Patents Filed / Published
S. No. Patent Details
  1.  
Synthesis of New Potent Aromatase Inhibitors Through Biocatalysis of Anti-Cancer Drugs, Atamestane, Drostanolone Enanthate, and Exemestane; Atia-tul-Wahab, M. Iqbal Choudhary, Mahwish Siddiqui, Nimra Naveed Shaikh, Nisha Khan, and Atta-ur-Rahman; US-Patent Application No. 17/199,481, Filing Date: 12/03/2021.
  1.  
New Potent Aromatase Inhibitors Through Fungal Transformation of Anti-Cancer Drug Testolactone: An Approach Towards the Treatment of Breast Cancer; M. Iqbal Choudhary, Atia-tul-Wahab, Mahwish Siddiqui, Nimra Naveed Shaikh, Sammer Yousuf, and Atta-ur-Rahman; US-Patent Application No. 17/177,209, Filing Date: 17/02/2021.
  1.  
Nasally Administered Pharmaceutical Composition for the Treatment of Epilepsy and Related Disorders; Farzana Shaheen, Atta-ur-Rahman, M. Iqbal Choudhary, Shabana U. Simjee, and Zehra Batool; US-Patent Serial No. 16/849,804, Patent Ref. 2020-0402, Filing Date: 16/04/2020.
  1.  
Apomorphine Plus Buspirone Combination for Memory Revival; Huma Ikram, Darakhshan J. Haleem, and Rumaisa Zakir; US-Patent Publication No. 2020/0038393 A1, Publication Date: 06/02/2020, US-Patent Application No. 16/053596, Filing Date:  02/08/2018.
  1.  
Non-Addictive Morphine Plus Buspirone Combination for the Treatment of Pain; Darakhshan J. Haleem, Shazia Nawaz, Tabinda Salman, and M. Iqbal Choudhary; US-Patent Publication No. 20170266184 A1Publication Date: 09/21/2017, Application No. 15/070,722, Filing Date: 03/15/2016.
  1.  
4-Hydroxybenzohydarzide-A New Class of Angiogenic Enzyme Thymidine Phosphorylase Inhibitors; M. Iqbal  Choudhary, Sumaira Javaid, Khalid M. Khan, Syed M. Saad, Atia-tul-Wahab, and Atta-ur- Rahman; US-Patent Publication No. 20170246130 A1Publication Date: 08/31/2017Application No. 15/053,887, Filing Date: 02/25/2016.
  1.  
4-[2-(Dipropylamino) ethyl]-1,3-dihydro-2H-indol-2-one (Ropinirole) a New Inhibitor of Jack bean Urease Enzyme: An Example of Drug Repurposing; Jalaluddin Azam Jalal Khan, M. Iqbal Choudhary, Maryam Abdu Abdullah Al-Ghamdi, Etimad Huwait, Atia-tul-Wahab, and Sumaira Javaid; US-Patent Publication No. 20170252323 A1, Publication Date: 09/07/2017Application Number: 15/061,280, Filing Date: 03/04/2016.
  1.  
Potent Inhibitors of Human Carbonic Anhydrase II and Bovine Carbonic Anhydrase II and their Mechanism of Action; M. I. Choudhary, M. Saleem, A. S. Bhatti, Atia-tul-Wahab, A. Khan, and Atta-ur-Rahman; US-Patent Publication No. 20170073306 A1, Publication Date: 03/16/2017, Application No. 14/854,981, Filing Date: 9/15/2015.
  1.  
In-Silico Based Techniques in the Identification of Potent ß-Glucoronidase Inhibitors; Maria Yousuf, Zaheer-ul- Haq, Nimra Naveed Shaikh, and M. Iqbal  Choudhary; US-Patent Publication No. 2017/0009272 A1, Publication Date: 01/12/2017Application No. 14/794,621, Filing Date: 07/08/2015.
  1.  
Reversal of Insulin Resistance and Dyslipidemia in High-Fat Diet-Induced Obese Rat Models by Physalis Minima L. Extract; Sammer Yousuf, Rehana Noshin, and M. Iqbal Choudhary; US-Patent Publication No. 2016/0220626 A1Publication Date: 08/04/2016, Application No. 14/609,224Filing Date: 01/29/2015.
  1.  
Synthesis and Biological Studies of an Isomeric Mixture of (E/Z) Isoxylitones and Its Analogues; Atta-ur-Rahman, M. Iqbal Choudhary, Farzana Shaheen, Shabana Usman Simjee, Noureen Khan, Saima M. Malhi, Syed Uzair Ali Shah, and M. Nadeem Ashraf; US-Patent Publication No. 2015/0148417 A1Publication Date: 05/28/2015, Application No. 14/609/211, Filing Date: 1/29/2015.
  1.  
Thiourea Derivatives as a-Chymotrypsin Inhibitors; Atta-ur-Rahman, M. Iqbal Choudhary, Bishnu P. Marasini, Khalid M. Khan, F. Sheikh, and Atia-tul-Wahab; US-Patent Publication No. 2015/0080580 A1Publication Date: 3/19/2015, Application No. 14/030,817, Filing Date: 09/18/2013.
  1.  
Anti-Glycation Properties of Oxindole Derivatives; M. Iqbal Choudhary, Saima Rasheed, Nessar Ahmed, Khalid M. Khan, Momin Khan, Atta-ur-Rahman, and Atia-tul-Wahab; US-Patent Publication No. 2015/0038543 A1, Publication Date: 2/5/2015, Application No. 13/954,648, Filing Date: 07/30/2013.
  1.  
Patulitin A Potent Anti-TNF-A and Antiarthritic Compound from Tagetes Patula; M. Ahmed Mesaik, Almas Jabeen, Shaheen Faizi, Shabana U. Simjee, Samina Bano, and Lubna; US-Patent Publication No. 2015/0025131 A1, Publication Date: 1/22/2015, Application No. 13/944,387, Filing Date: 7/17/2013.
  1.  
Process for Microwave-Assisted Synthesis Of 2-(2’,4’-Dichloroanilino) Benzoic Acid As An Anti-Leishmanial Agent; Khalid M. Khan, Mehwish Manzoor, Nida Ghouri, Sammer Yousuf, M. Iqbal Choudhary, and Shahnaz Perveen; US-Patent Application No. 14/520,012Filing Date:  10/23/2014.
  1.  
Quinazolines as β-Glucuronidase Novel Inhibitors; M. Iqbal Choudhary, Khalid M. Khan, Syed Muhammad Saad, Nimra Naveed Sheikh, Sammer Yousuf, and Atta-ur-Rahman; US-Patent Publication No. 2014/0256754 A1, Publication Date: 9/11/2014, Application No. 13/789,021, Filing Date: 03/07/2013.
  1.  
Immunosuppressive Compounds; M. Ahmed Mesaik, Khalid M. Khan, Omer M. Abdalla, Fazal Rahim, A. Shukralla, Khalid, Zaheer-Ul-Haq, Shahnaz Perveen, Samreen Soomro, and Sobia Ahsan Halim; US-Patent Publication No. 2014/0378515 A1Publication Date: 12/25/2014, Application No. 13/921,705, Filing Date: 6/19/2013.
  1.  
Heterocyclic Schiff’s Bases as Novel and New Antiglycation AgentsS. Ibrahim Al-Resayes, I. Warad, M. A. Al-Nuri, M. Iqbal Choudhary, Atia-tul-Wahab, and S. Rasheed; US-Patent Publication No. 2014/0221429 A1, Publication Date: 08/07/2014, Application No. 13/757,956, Filing Date: 02/04/2013.
  1.  
Novel Hydroxylated Enantiomers of (-) 3a,6,6,9a-Tetramethylperhydronaphtho[2,1-b] Furan as Perfuming Agents Derived from a Fungal Fermentation Process; Atta-ur-Rahman, M. Iqbal Choudhary, Syed Ghulam Musharraf, and Amtul Sami; US-Patent Publication No. 2012/0301956 A1Application No. 13/115991Publication Date: 11/29/2012, Filing Date: 05/26/2011.
  1.  
Tyrosinase Enzyme Inhibitors from Fungal Hydroxylation of Tibolone; Atta-ur Rahman, M. Iqbal Choudhary, Syed Adnan Ali Shah, and Mahmud Tariq Hassan Khan; US-Patent Publication No. 20090136434 A1, Application No. 11/944476, Publication Date: 05/28/2009, Filing Date: 11/23/2007.
  1.  
α-Glucosidase Inhibitors from Fungal Hydroxylation of Tibolone and Hydroxytibolones; Atta-ur Rahman, M. Iqbal Choudhary, Syed Adnan Ali Shah, and Shamsun Nahar Khan; US-Patent Publication No. 20090137542 A1Application No. 11/944,475, Publication Date: 05/28/2009, Filing Date: 11/23/2007.
  1.  
Natural Novel Antioxidants; M. Iqbal Choudhary, Sajjad Ali, Vinitha M. Thadani, and Veranja Karunaratne; US-Patent Publication No. 20090048332 A1Application No.  11/838567, Publication Date: 02/19/2009, Filing Date: 08/14/2007.
  1.  
New α-Glucosidase Inhibitors and Antibacterial Compounds from Myrtus communis L.; Atta-ur Rahman, M. Iqbal  Choudhary, Farzana Shaheen, Manzoor Ahmad, Shamsun Nahar Khan, and Shazia Anjum; US-Patent Publication No. 20080269510 A1Application No. 11/306345, Publication Date: 10/30/2008, Filing Date: 12/23/2005.
  1.  
Novel α-Glucosidase Activator, Pulicarside 1; Viqar Uddin Ahmad, M. Iqbal Choudhary, Nasir Khan, and Shamsun Nihar KhanUS-Patent Publication No. 20080274987 A1, Application No. 11/422833, Publication Date: 11/06/2008, Filing Date: 06/07/2006.
  1.  
Novel α-Glucosidase Inhibitor from Tabernaemontana dichotoma; Mirihanage Don Jayantha Wijayabandara, Shamsun Nahar Khan, and M. Iqbal  Choudhary; US-Patent Publication No. 20080103201 A1,  Application No. 11/553465, Publication Date: 05/01/2008, Filing Date: 10/26/2006.
  1.  
Antibiotic Bushrin; Nuzhat Ahmed, Bushra Uzair, Viqar Uddin Ahmad, and Farzana Kousar; US-Patent Publication No. 20080090900 A1Application No. 11/548715, Publication Date: 04/17/2008, Filing Date: 10/12/2006.
  1.  
Anti-Hyperurecemic Agent 4-Pyradine Carboxylic Acid Hydrazides; M. Iqbal Choudhary, H. Zafar, K. M. Khan, Atta-ur Rahman, and Atia-tul-Wahab, and H. Khan; US-Patent Application Ref. 2014.0527.
  1.  
New Treatment of Diabetes Mellitus; Viqar Uddin Ahmad, Nasir Rasool, M. Iqbal Choudhary, and Shamsun Nihar Khan; US-Patent Publication No.  20070287674 A1Application No. 11/309,013, Publication Date: 12/13/2007, Filing Date: 06/08/2006.
 
 
List of Non-US Patents
S. No. Patent Details
  1.  
New Pyrazolone Derivative as a Promising Immunomodulatory Agent; Almas Jabeen, Tariq Ahmad Baig, Khalid Mohammed Khan, and Sahar Yousuf; Pakistan Patent Application No. 521/2021, Filing Date: 12/07/2021.
  1.  
Peptide Dendrimers Based on Temporin SHa as Anticancer and Antimicrobial Agents; Farzana Shaheen, Arif Iftikhar Khan, Muhammad Nadeem ul Haque, Rukesh Maharjan, Shabana U. Simjee, Hamza Olleik, Marc Maresca, and M. Iqbal Choudhary; Pakistan Patent Application No. 442/2021, Filing Date: 14/06/2021.
  1.  
New Sulfadimethoxine Derivatives as an Immunomodulatory Agent; Almas Jabeen, Tariq Ahmad Baig, Hina Siddiqui, and Haroon M. Haniffa; Pakistan Patent Application No. 441/2021, Filing Date: 14/06/2021.
  1.  
Bio-catalyzed Synthesis of New Aromatase Inhibitors Trough Structural Modifications of Anticancer Drug Formestane; Atta-ur-Rahman, M. Iqbal Choudhary, Rabia Farooq, Atia-tul-Wahab, and Nimra Naveed Shaikh; Pakistan Patent Application No. 340/2021, Filing Date: 04/05/2021.
  1.  
1, 2, 3, Triazole-Modified Analogues of Hydrochlorothiazide as Potent In-Vitro Inhibitors of α-Glucosidase Enzyme; Hina Siddiqui, M. A. A. Baheej, Saeed Ullah, Haroon M. Haniffa, Shazia Iqbal, Atia-tul-Wahab, and M. Iqbal Choudhary; Pakistan Patent Application No. 325/2021, Filing Date: 27/04/2021.
  1.  
Anti-Alzheimer’s Butyrylcholinesterase Inhibitors and Anti-Leishmanial New Derivatives of 4-Aminoantipyrine; Hina Siddiqui, Fazila Rizvi, Sheeba Wajid, Atia-tul-Wahab, Sammer Yousuf, Atta-ur-Rahman, and M. Iqbal Choudhary; Pakistan Patent Application No. 244/2021, Filing Date: 26/03/2021.
  1.  
Fetal Hemoglobin Reactivation Activity of Cilostazol (6-[4-(1-Cyclohexyl-1H-Tetrazol-5-yl)Butoxy]-3,4-Dihydro-2(1H)-Quinolinone); Syed Ghulam Musharraf, Hamad Ali, and Faisal Khan; Pakistan Patent Application No. 232/2021, Filing Date: 24/03/2021.
  1.  
New Cyclic Peptides as Nitric Oxide Inhibitors; Farzana Shaheen, Aaqib Ullah, Almas Jabeen, Sidrah Shams, and M. Iqbal Choudhary; Pakistan Patent Application No. 212/2021, Filing Date: 22/02/2021.
  1.  
Indole-Linked 1,2,3,-Triazole Derivatives Alleviate MGO-Mediated Protein Glycation to Prevent Diabetopathies; M. Iqbal Choudhary, Humera Jahan, Nimra Naz Siddiqui, Fatima Z. Basha, Shazia Iqbal, and Atta-ur-Rahman; Pakistan Patent Application No. 137/2021, Filing Date: 16/02/2021.
  1.  
Prevention and Teatment of SARS-CoV-2, Infection by Mentha Piperita, and Flos Chrysanthemi Extracts Alone, and Their Combination, Atta-ur-Rahman, Saba Farooq, Atia-tul-Wahab, and M. Iqbal Choudhary, Pakistan Patent Application No. 125/2021, Filing Date: 10/02/2021.
  1.  
Synthesis of Non-Toxic, Anti-Viral Desmuramyl Peptides Containing Xanthine Scaffolds; Farooq Ahmad Khan, Rahila Khanam, Sana Yaqoob, and Muhammad Rashid, Pakistan Patent Application No. 108/2021, Filing Date: 03/02/2021.
  1.  
Synthesis of Non-Toxic, Bio-Active Compounds from Isonicotinic Acid; Farooq Ahmad Khan, Nourina Nasim, Sana Yaqoob, and Rahila Khanam, Pakistan Patent Application No. 62/2021, Filing Date: 18/01/2021.
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Furan Conjugated Peptidomimetic as Promising Anticancer Agent; Farzana Shaheen, Hunain Ali, and Almas Jabeen; Pakistan Patent No. 143700, Pakistan Patent Application No. 640/2019, Patent Date: 13/01/2021.
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Indole-based Thiazole Derivatives as Novel Antiglycation Agents for the Treatment and Prevention of Late Diabetic Complications; Humera Jahan, M. Iqbal Choudhary, Umair Aleem, Asad Ullah, Bina S. Siddiqui, Sabira Begum, and Atta-Ur-Rahman, Pakistan Patent Application No. 43/2021, Filing Date: 05/01/2021.
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New Aromatase Inhibitors through Aspergillus niger-mediated Transformation of Anabolic Drug Mibolerone; M. Iqbal Choudhary, Atia-tul-Wahab, Mahwish Siddiqui, Nimra Naveed Shaikh, and Atta-ur-Rahman; Pakistan Patent Application No. 687/2020, Filing Date: 08/10/2020.
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New Potent Aromatase Inhibitors Through Fungal for Transformation of Anti-Cancer Drug Testolactone: An Approach Towards the Treatment of Breast Cancer; M. Iqbal Choudhary, Atia-tul-Wahab, Mahwish Siddiqui, Nimra Naveed Shaikh, Sammer Yousuf, and Atta-ur-Rahman; Pakistan Patent Application No. 621/2020, Filing Date: 24/09/2020.
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Nasal Formulation of (Z)-2-(3,4,4-Trimethyl-2-Cyclohexan-1-ylidene) Acetic Acid for the Treatment of Epilepsy and Related Disorders; Farzana Shaheen, Atta-ur-Rahman, M. Iqbal Choudhary, Shabana U. Simjee, and Zehra Batool; Pakistan Patent Application No. 505/2020, Filing Date: 30/07/2020.
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Spirulina Supplement Ameliorates the Psychosis-Like Symptoms in an Animal of Schizophrenia; Zehra Batool, Saida Haider, Sidrah Shahzad, Saiqa Tabassum, Laraib Liaquat, Syeda Madiha, Sadia Sadir, and Asia Afzal; Pakistan Patent Application No. 506/2020, Filing Date: 30/07/2020.
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Synthesis of a New Potent Aromatase Inhibitor through Biocatalysis of Anticancer Drug Atamestane, M. Iqbal Choudhary, Atia-tul-Wahab, Mahwish Siddiqui, Nimra Naveed Shaikh, and Atta-ur-Rahman; Pakistan Patent Application No. 475/2020, Filing Date: 22/07/2020.
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Repurosing of Tenofovir Disoproxil Fumarate for the Treatment of β-Thalassemia and Sickle Cell Anemia; Syed Ghulam Musharraf, Faisal Khan, and Hamad Ali; Pakistan Patent Application No. 445/2020, Filing Date: 01/07/2020.
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Methods for Increasing the Content of Flavonols and their Antioxidant Properties in Grape Fruits, Fang Fang, Fengzhong Wang, Donghui Wang, Yan Wang, Cencan Xing, and Lijing Zhang, Chinese Invention Patent Application No. CN106723206 A, Filing Date: 14/2/2020.
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3,4-Dihydroxy-Phenylethyl-3’-O-Benzoyl-D-Glucopyranoside as New Anti-Inflammatory Compound; Bina S. Siddiqui, Talea Sana, Almas Jabeen, and Sabira Begum; Pakistan Patent Application No. 68/2020, Filing Date: 28/01/2020.
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Repurposing of Acyclovir for the Treatment of β-Thalassemia and Sickle Cell Anemia; Syed Ghulam Musharraf, M. Iqbal Choudhary, Atta-ur-Rahman, and Hamad Ali; Pakistan Application No. 868/2019, Filing Date: 24/12/2019.
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Immunomodulatory Amphiphilic Desmuramyl Peptides; Farooq Ahmad Khan, and Zi-Hua Justin Jiang; Pakistan Patent Application No. 844/2019, Filing Date: 16/12/2019.
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Phenylethanoid Glycoside Anti-Inflammatory Compound; Bina S. Siddiqui, Talea Sana, Almas Jabeen, Tariq Ahmad Baig, and Sabira Begum; Pakistan Patent Application No. 248/2019Filing Date: 22/4/2019.
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Urease Inhibitory Iridoid Glycoside Compound; Bina S. Siddiqui, Talea Sana, Majid Khan, and Sabira Begum; Pakistan Patent Application No. 520/2019Filing Date: 22/7/2019.
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A New Dietary Health Supplement for the Management and /or Treatment of Age Related Neurodegenerative Diseases Including Parkinson’s Disease, M. Iqbal Choudhary, Atta-ur-Rahman, Atia-tul-Wahab, and Humaira Zafar, Patent Application No. 578/2019Filing Date:26/8/2019.
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Detection of Familial Breast Cancers Caused by BRCA2 c.5642delAATC Mutation; S. Ajaz, S. Z. Zaidi and S. Mehboob Ali; Pakistan Patent Application No. 846/2018, Filing Date: 11/02/2018.
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A Process for the Extraction of Phosphoric acid by Amyl Alcohol; Mohammad A. Khan, Mohammad Arif, Imtiaz-ud-Din, Khalid Mohammad Khan, Nida Ambreen and Shahnaz Perveen; Patent No. 142652, Government of Pakistan (2018).
  1.  
Novel Class of Aminoantipyrine Based Bactericidal Nonionic Surfactants; Muhammad Raza Shah, Muhammad Imran, Farhat Ullah, Heyam Saad Ali, Shafiullah, and Imdad Ali; Pakistan Patent Application No. 321/2018.
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Novel Double-Tailed Glycoside Nonionic Surfactant For Niosomal Drug Delivery; Muhammad Raza Shah, and Muhammad Imran; Pakistan Patent Application No. 322/2018.
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Synthesis of C-Glycoside Of 4-O-Methyl Galic Acid Based Double-Tailed Nonionic Surfactant As Nano-Scale Drug Loading And Delivery System; Muhammad Raza Shah, and Muhammad Imran; Pakistan Patent Application No. 323/2018.
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A New Series of Thiourea Containing Bacteriolytic Nonionic Surfactants; Muhammad Raza Shah, Shafiullah, Mohammad Shoaib, Syed Wadood Ali Shah, Heyam Saad Ali, Muhammad Imran, and Salim Saifullah ; Pakistan Patent Application No. 324/2018.
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2-4-Dinitroanilino-Benzoic Acid: Novel Insulinotropic Agent for the Treatment of Diabetes, Humera Jahan; M. Iqbal Choudhary, Mehwish Manzoor, Khalid M. Khan, and Atta-ur-Rahman; Pakistan Patent Application No.536/2016, US-Patent Publication No. 2017.0620, Application No. 15/682,623, Filing Date: 08/22/2017, Publication Date: 28/08/2017.
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A Process For Preparing An Efficient and Safe Hepatoprotective Composition from Methanolic Extract of Ceasalpinia bonduc; Ahsana Dar, Shaheen Faizi, M. Hafizur Rahman, Muhammad Ahmed Mesaik, Lubna Avesi, Muhammad Ali Versiani, and Farah Naz; Pakistan Patent Application No. 233/2015.
  1.  
A Process for the Qualitative Analysis of Cations of Metal Salt by Microwave-Spark Emission; Khalid M. Khan, Zahid Hussain, Khadim Hussain, and Shahnaz Parveen; Pakistan Patent No. 141828, Dated: 24/12/2014.
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Reversal of Haloperidol-Induced Parkinsonism and Tardive Dyskinesia by Buspirone; Darakhshan Jabeen Haleem, Erum Shireen, Farhat Batool, Huma Ikram, Noreen Samad, Saida Haider, and MA Haleem; Pakistan Patent Application No. 364/2011.
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Reversal of Haloperidol-Induced Parkinsonism and Tardive Dyskinesia by Mianserin; Darakhshan Jabeen Haleem Erum Shireen, Farhat Batool, Huma Ikram, Qurat-Ul Ain Inam, Tahira Perveen, and MA Haleem; Pakistan Patent Application No. 363/2011.
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Protective Effects of Aqueous Fruit Extract From Sea Buckhorn (Hippophae Rhammoides Ssp Turkestanica); Darakhshan Jabeen Haleem, Farhat Batool Asad Hussain Shah, Dilnawaz Ahmed, And M A Haleem; Pakistan Patent Application No. 362/2011.
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5-HT1A Agonist 8-OH-DPAT Attenuates Extrapyramidal Symptoms Associated With Antipsychotics; Darakhshan Jabeen Haleem, Farhat Batool, Huma Ikram, Erum Shireen, MA Haleem; Pakistan Patent Application No. 361/2011.
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Buspirone Can Normalize Apomorphine-Induced Addiction; Darakhshan Jabeen Haleem, Huma Ikram, Farhat Batool, and Erum Shireen; Pakistan Patent Application No. 360/2011.
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Low But Not High Dose of Buspirone Could Attenuate Apomorphine-Induced Sensitization; Darakhshan Jabeen Haleem, Huma Ikram, and MA Haleem; Pakistan Patent Application No. 359/2011.
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Development of Process for Preparation of New Spasmolytic Composition from Psidium guajava Leaves; Sabira Begum, Bina S. Siddiqui, S. I. Hassan, A. H. Gilani, and M. N. Ghayur; CBR No:1, The Patent Office Govt. of PakistanPatent Serial No: 140597, 2010.
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A Process For Preparation of A Herbal Composition Useful As Stabilizer For Edible Oils; Shahid Iqbal, and M. Iqbal Bhanger; Pakistan Patent No. 140293, Dated: 30/3/2010.
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A Herbal Antioxidant Composition For Deriving Gum Stability; Shahid Iqbal, and M. Iqbal Bhanger; Pakistan Patent No. 140101, Dated: 2/2/2010.
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A Process for the Preparation of Pesticidal Composition Biosal from the Dried Neem Seeds Kernel; Bina S. Siddiqui, S. Naeem-ul-Hasan Naqvi, Syed Tariq Ali, and Shaheen Faizi; The Patent Office Govt. of PakistanPatent Serial No. 140326, 2010.
  1.  
A Process for the Synthesis of New Anti-Tuberculosis Agents; Sabira Begum, S. N. Ali, and Bina. S. Siddiqui; Pakistan Patent Application No. 1040/2009.
  1.  
Antifungal Formulation from Kalidium foliatum; Bina S. Siddiqui, Zh. Zh. Karzhaubekova, G. Sh. Burasheva, and N. A. Sultanova; Patent Application No. 56218, Kazakhistan, 2009.
  1.  
Antibacterial Formulation from Kalidium foliatum; Bina S. Siddiqui, Zh. Karzhaubekova, G. Sh. Burasheva, and N. A. Sultanova; 2009.
  1.  
Process of Extraction of Bergenin from the Leaves of Flueggea leucopyrus Willd (Katupila) as a Novel Method of Obtaining Bergenin; M. D. J. Wijayabandara and Muhammad Iqbal Choudhary; Sri Lanka Patent No. 15566, Dated: 13/10/2009.
  1.  
N-Acetyl-2-Aminophenol; Sheikh Arshad Saeed, and Shahzada Omar Saeed, UK Patent on Orthacetamol; U.K. Patent No. 2405092, 2008.
  1.  
Anti-Platelet Aggregation Compositions; Sheikh Arshad Saeed, and Shahzada Omar Saeed; U.KPatent No. GB 2407040, 2007.
  1.  
Neemex, a Biofertilizer-Cum-Pesticide Based on The Dried Fruits Seeds of Azadirachta indica A. Juss; Bina S. Siddiqui, S. T. Ali, and S. K. Ali; CBR No. 3022The Patent Office Govt. of Pakistan, 2007.
  1.  
Bioaman–A Botanical Insecticidal Composition for Household Use Based on The Dried Fruits or Kernel of Azadirachta indica A. Juss; Bina S. Siddiqui, S. N. H. Naqvi, S. T. Ali, and S. K. Ali; CBR No. 3021The Patent Office Govt of Pakistan, 2007.
  1.  
2-Hydroxyacetanilide to its Pharmaceutical Composition Containing it and its Use as Anti-Inflammatory Analgesic Anti-Pyretic and Anti-Platelet Agent; Sheikh Arshad Saeed, and Shahzada Omar Saeed; Pakistan Patent No. 138941, 2007.
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The Manner of Obtaining Remedy Posses Antifungal Activity; B. K. Yeskalieva, M. Iqbal Choudhary, G. Sh. Burasheva, N. A. Sultanova, and Zh. A. Abilov; Kazakhstan Patent No. 51835, 2005.
  1.  
The Manner of Obtaining Remedy Posses Antibacterial Activity; B. K. Yeskalieva, M. Iqbal Choudhary, G. Sh. Burasheva, N. A. Sultanova, and Zh. A. Abilov; Kazakhstan Patent No. 51840, 2005.
  1.  
A Process For Preparing Efficient and Safe Antioxidant and Analgesic Composition Containing Xanthone-C-Glucoside Mangiferin from Bombax ceiba; Ahsana Dar, Shaheen Faizi, S. Naqvi, T. Roome, S. Zikr-ur-Rehman, and M. Ali; Patent Application No. 633 05, 2005.
  1.  
A Simple Method of Isolation of an Antioxidant Patuletin in Large Quantity From Flowers of Tagetes Patula; Ahsana Dar, Shaheen Faizi, S. Naqvi, H. Siddiqi, A. Naz, and  S. Bano; Pakistan Patent, 2005.
  1.  
The Manner for Obtaining of Antioxidant Polyphenols Complexes from Tamarix laxa, A. K. Umbetova; M. Iqbal Choudhary, G. Sh. Burasheva, N. A. Sultanova, and Zh. A. Abilov; 2006.
  1.  
The Manner for Obtaining of Antibacterial Polyphenols Complexes from Kamphorosma monspeliacum, A. K. Umbetova, M. Iqbal Choudhary, G. Sh. Burasheva, N. A. Sultanova, and Zh. A. Abilov; 2006.
  1.  
Biosal-a Pesticidal Composition Based on The Whole Fruits of Azedirachta indica A. Juss, B. S. Siddiqui, S. N. H. Naqvi, S. T. Ali, and Shaheen Faizi;  Patent Serial No. 2181, The Patent Office Govt. of PakistanPatent Application No. 1222 06, 2006.
  1.  
Agrosal-a Pesticidal Composition Based on The Whole Dry Fruits or kernel of Azadirachta Indica A. Juss, Bina S. Siddiqui, S. N. H. Naqvi, Syed Tariq Ali, Shaheen Faizi, and Syed Kashif Ali; CBR No. 2181The Patent Office Govt of Pakistan, 2006.
  1.  
Development of a Method For The Production Of Bio-Diesel; Bina S. Siddiqui, Syed Tariq Ali, and Jafar Nazir Usmani; CBR No. 2180The Patent Office Govt. of Pakistan, 2006.
  1.  
A Process for the Development of an Insecticidal Composition Based on Neem Azadirachta indica Fruit Coats; Bina S. Siddiqui, S. N. H. Naqvi, and Shaheen Faizi; Pakistan Patent No. 138573The Patent Office Govt. of Pakistan, 2003.
  1.  
A Process for the Preparation of a Herbal Composition for the Skin Treatment of Farm and Pet Animals; Bina S. Siddiqui, Ahsana Dar, and Shaheen Faizi; Pakistan Patent No. 138572, The Patent Office Govt. of Pakistan, 2003.
  1.  
Some Fractions of Polyphenols of Tamarix ramosissima Tamaricaceae Posses Antifungal Activity; N. A. Sultanova, T. Makhmoor, V. B. Omurkamzinova, M. Iqbal Choudhary, Atta-ur-Rahman, and Zh. A. Abilov; Patent No. 11936,А 61К 35/78, Bulletin No. 9, Dated: 16/09/2002.
  1.  
Nematicidal Composition NIMATICIDOL Based on The Aerial Parts of Lantana camara Linn.; Sabira Begum, Bina S. Siddiqui, Aneela Wahab, and Fatima Qamar; Serial No. 136887, The Patent office Govt. of Pakistan, 2001.
  1.  
Process for the Osmo-Drying of Fruits and Vegetables for the Production of New Snacks Products; Atta-ur-Rahman, M. Iqbal Choudhary, and Juveria Siddiqui; Pakistan Patent Application No. 353/2000, Dated: 22/04/2000.
  1.  
A Process For Preparing a Composition To Cure Eczema From Melia azedarach Linn.; Shaheen Faizi, Bina S. Siddiqui, R. Saleem, S. I. Ahmed, and A. Wasi; Patent Application No. 656/2000, S. I. No. 137331, 2000.
  1.  
Antihypertensive Medicine Based on Sahjana Moringa olifera; Shaheen Faizi, Bina S. Siddiqui, A. H. Gilani, and Rubina Saleem; Serial No. 136438, The Patent Office Govt  of Pakistan, 2000.
  1.  
Antihypertensive Medicine Aloedin Based on Aloe Barbadensis Mill; Shaheen Faizi, Rubeena Saleem, Bina S. Siddiqui, Ahsana Dar, S. Iqbal Ahmed,  and M. H. Qazi; Serial No. 136463, The Patent Office Govt. of Pakistan, 2000.
  1.  
Novel Formulation of The Antimicrobial Composition, Amoxycassia Based on The Synergistic Activity of Cassia fistula and Amoxicillin; Shaheen FaiziS. U. Kazmi, and N. Hasan Ali; Patent Application No. 1121/99, Patent No. 137124.
  1.  
A Process For Preparing an Antihypertensive Composition Containing Anthraquinone From Aloe Barbadensis Mill; R. Saleem, Shaheen Faizi, Bina S. Siddiqui, Ahsana Dar, S. I. A., and M. H. Qazi; Pakistan Patent Application No. 862/98, 1998.
  1.  
A Process For Preparing an Antihypertensive Composition Containing Xanthone C-Glucoside Mangiferin From Bombax ceiba Linn.; Shaheen Faizi, R. Saleem, M. Ali, S. I. Ahmed, and M. H. Qazi; Pakistan Patent No. 136464, Patent Application No. 814/98, 1998.
  1.  
Antihypotensive Medicine brassico Based on brassica rapa sb. sp. Campestris, Shaheen Faizi; A. H. Gilani, Irfanullah, Farzana Shaheen, and S. Bibi; Pakistan Patent S. I. No. 136437, Patent Application No. 871/98, 1998.
  1.  
Antihypertensive Composition Containing Thiocarbamate Glycosides From Moringa oleifera; Shaheen Faizi, Bina S. Siddiqui, A. H. Gilani, and R. Saleem; Pakistan Patent Application No. 872/98, 1998.
  1.  
A Novel Cholesterol-Lowering Edible Oil Composition Comprising of Garlic Extract; Atta-ur-Rahman, and M. Iqbal Choudhary; Pakistan Patent No. 135653, Dated: 23/01/1997.
  1.  
A Preparation of Novel Composite Essential Oil Mixture Which is Identical to Famous Garam Masala Mixure of Spices; Atta-ur-Rahman, M. Iqbal Choudhary, Aftab Ahmed, and Afgan Farooq; Pakistan Patent No. 135652, Dated: 23/01/1997.
  1.  
The Development of Simple Process for the High Yield Extraction of Essential Oils From Different Aromatic Spices, Flowers and Nuts; Atta-ur-Rahman, M. Iqbal Choudhary, and Aftab Ahmed; Pakistan Patent No. 135689, Dated: 16/02/1997.
  1.  
Pesticidal Composition Based on Neem; Bina S. Siddiqui, N. H. Naqvi, and Shaheen Faizi; Pakistan patent No. 133662, 1995.
  1.  
A Processes For Preparation of New Cytotoxic Composition From Nerium Oleander; Bina S. Siddiqui, and Sabira Begum; Patent No. 133661, The Patent Office Govt. of Pakistan, 1995.
  1.  
Plant-Based Anti-Diarrheal Drug and Abdominal Pain Reliever; Atta-ur-Rahman, and M. Iqbal Choudhary; Pakistan Patent No. 236/92, Dated: 18/5/1992.
  1.  
Preparation of Aluminum Based Demulsifiers for Oil- Water Washing in Furnace Oil Turbine Power Stations; Atta-ur-Rahman, M. Iqbal Choudhary, and Khalid M. Khan; Pakistan Patent No. 213/92, Dated: 10/5/1992.
  1.  
A Rapid Procedure for the Isolation of Vinblastine from the Leaves of Catharanthus roseus; Atta-ur-Rahman, J. Fatima and A.N; Pakistan Patent No. 128340, Dated: 14/2/1984.
  1.  
A New Procedure for the Isolation of Vinblastine from the Leaves of Catharanthus roseus, Atta-ur-Rahman and M. Bashir; Pakistan Patent No. 128638, Dated: 18/4/1983.
  1.  
Methods for the Syntheses of Vinblastine, 20-Epivinblastine (Vinrosidine), 15-Hydroxy-20-Deoxyvinblastine, Vincristine and other Novel Intermediates; Atta-ur-Rahman; Pakistan Patent No. 126852, Dated: 14/2/1978.
  1.  
Synthesis of Vinblastine, Vincristine and Vinrosidine - By Converting Catharanthine To Its (N)-Oxide Derivatives Followed By Treatment With Vindoline; Atta-ur-Rahman; Germany Patent No. 261486, Dated: 13/10/1977.
  1.  
The Synthesis of Vinblastine, Vincristine and Vinrosidine; Atta-ur-Rahman; U.K. Patent No. 1551054, Dated: 7/5/1976.
  1.  
A Process for The Production of Mononitroajmaline; Salimuzzaman Siddiqui, and Viqar Uddin Ahmad; Pakistan Patent No. 122593, Dated: 4/2/1972.
  1.  
Improvement in and with Relation to the Production of C-Nitrosoajmaline; Salimuzzaman Siddiqui, and Viqar Uddin Ahmad; Pakistan Patent No. 122840, Dated: 25/1/1972.



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