Cyclic Peptides Anticancer Drug Delivery13/07/21
Prof. Dr. Keykavous Parang Associate Dean of Research, Graduate Studies, and Global Affairs Professor of Medicinal Chemistry and Pharmacology, Chapman University, USA
In this presentation, the Speaker will introduce different cyclic peptide platforms that have been developed for anticancer drug delivery. The goal is to further optimize the peptide structures to assure the efficient delivery and safety of anticancer drugs for clinical use.
Target Audience: This webinar is open to academicians, scientists, and general public from all the member OIC states and beyond.
Profile of the Speaker: Dr. Parang is Associate Dean of Research, Innovation, and Global Affairs and a Full Professor of Medicinal Chemistry and Pharmacology at Chapman University School of Pharmacy in Irvine, California. He earned a Pharm.D. degree from Tehran University of Medical Sciences in 1989. He received his Ph.D. in medicinal chemistry from the Faculty of Pharmacy at the University of Alberta in 1997, followed by a postdoctoral study in the field of solid-phase organic synthesis in the Department of Chemistry. He pursued additional postdoctoral studies at Rockefeller University in New York and Johns Hopkins University in Baltimore in bioorganic chemistry. He joined the University of Rhode Island in October 2000 and became a full professor in July 2008. He served as the Program Coordinator of Rhode Island IDeA Network of Biomedical Research Excellence (RI-INBRE) NIH program (2012-2013). He joined Chapman University to assist in establishing the School of Pharmacy. He is an author of 189 peer-reviewed publications, 10 patents, and 171 meeting abstracts.
Dr. Parang’s research can be described as applying synthetic organic chemistry to problems in biology. Specific areas currently under investigation include (1) using peptides as cell-penetrating molecular transporters in drug delivery; (2) designing protein kinase inhibitors; (3) developing multifunctional antiviral, anticancer, and antibacterial agents; and (4) designing peptide nanomaterials for nanomedicine. One major area currently under investigation is to design peptide nanomaterials for applications in drug delivery. The objective of this project is to design and evaluate peptide nanomaterials as cell-penetrating nuclear targeting agents or molecular transporters of bioactive cell-impermeable compounds. This study will document the potential for new hybrid peptide-drug assemblies that may be used for the non-covalent or covalent targeted delivery of bioactive molecules, including cell-impermeable compounds with biological significance. He is an author of 205 peer-reviewed publications, 13 issued or pending patents, and more than 180 meeting abstracts.
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